1: 2-(β,β-dibromovinyl)-2-naphthol With tetrabutyl ammonium fluoride in N,N-dimethyl-formamide T=20°C; 4 h; Sealed tubeInert atmosphere; 2: benzenesulphinic acid sodium salt With copper diacetate; triethylamine; palladium dichloride in N,N-dimethyl-formamide T=110°C; 12 h; Sealed tubeInert atmosphere;

tetrabutyl ammonium fluoride; palladium diacetate; triphenylphosphine in 1-methyl-pyrrolidin-2-one T=80°C; tandem elimination-addition-Hiyama coupling; 12 h;

1,10-phenanthroline; Cu(acetate)2*(x)H2O; sodium acetate; palladium diacetate in 1,2-dichloro-ethane T=110°C; 24 h; Molecular sieve;

bis(η3-allyl-μ-chloropalladium(II)); N,N,N′,N′-tetra(diphenylphosphinomethyl)pyridine-2,6-diamine; caesium carbonate in N,N-dimethyl-formamide T=130°C; Sonogashira Cross-Coupling; 24 h; Schlenk techniqueInert atmosphere;

water; copper(l) chloride in N,N-dimethyl-formamide Heating;

1: 94 percent / 4 h / Heating 2: 1.)Diisopropylamine, nBuLi, 2.)HI / 1)THF, -60 deg C, 20 min; 2)HOAc, reflux 4h View Scheme

1: palladium diacetate; triethylamine; triphenylphosphine / 80 °C / Inert atmosphere 2: [bis(acetoxy)iodo]benzene / acetonitrile / 2 h / 20 °C / Inert atmosphere View Scheme

n-butyllithium; hydrogen iodide; diisopropylamine 1)THF, -60 deg C, 20 min; 2)HOAc, reflux 4h; Yield given. Multistep reaction;