1: With 1-chloroethyl chlorocarbonate in 1,2-dichloro-ethane 2 h; Heating; 2: With methanol Heating;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11406361', constants.ctx, '0')">Wilkinson's catalyst</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '3587189', constants.ctx, '0')">hydrogen</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '635760', constants.ctx, '0')">toluene</a> <br />T=70&deg;C;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 76 percent / tetrahydrofuran / 0 &deg;C<br />2: 94 percent / P₂O₅ / toluene / Heating<br />3: 91 percent / H₂; (Ph₃P)3RhCl / toluene / 70 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 76 percent / tetrahydrofuran / 0 &deg;C<br />2: 94 percent / P₂O₅ / toluene / Heating<br />3: 91 percent / H₂; (Ph₃P)3RhCl / toluene / 70 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1: 70 percent / dimethylformamide / 70 &deg;C<br />2: 76 percent / tetrahydrofuran / 0 &deg;C<br />3: 94 percent / P₂O₅ / toluene / Heating<br />4: 91 percent / H₂; (Ph₃P)3RhCl / toluene / 70 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1: 70 percent / dimethylformamide / 70 &deg;C<br />2: 76 percent / tetrahydrofuran / 0 &deg;C<br />3: 94 percent / P₂O₅ / toluene / Heating<br />4: 91 percent / H₂; (Ph₃P)3RhCl / toluene / 70 &deg;C<br /> <br /> &nbsp;