triethylamine in dichloromethane T=0 - 20°C; 72 h;

sodium hydrogencarbonate in ethanol

sodium carbonate in dichloromethane; water 21 h; Product distribution / selectivity;

sodium hydroxide in methanol T=20°C; 2 h;

potassium carbonate in tetrahydrofuran; water; ethyl acetate

anhydrous sodium hydrogen carbonate; sodium chloride in methanol; dichloromethane

in 1,4-dioxane; dichloromethane

1.1: triethylamine / dichloromethane / 10 h / Reflux 2.1: lithium aluminium tetrahydride / tetrahydrofuran / 16 h 2.2: 0 °C 3.1: trifluoroacetic anhydride / tetrahydrofuran / 1 h / -78 °C 3.2: 60.33 h / -78 °C / Reflux 3.3: 2 h / 20 °C 4.1: 10 palladium on activated charcoal; hydrogen / ethanol / -78 °C / 760.05 Torr 4.2: 60.33 h / -78 °C / Reflux 4.3: 2 h / 20 °C 5.1: sodium hydrogencarbonate / ethanol View Scheme

1.1: trifluoroacetic anhydride / tetrahydrofuran / 1 h / -78 °C 1.2: 60.33 h / -78 °C / Reflux 1.3: 2 h / 20 °C 2.1: 10 palladium on activated charcoal; hydrogen / ethanol / -78 °C / 760.05 Torr 2.2: 60.33 h / -78 °C / Reflux 2.3: 2 h / 20 °C 3.1: sodium hydrogencarbonate / ethanol View Scheme

1.1: lithium aluminium tetrahydride / tetrahydrofuran / 16 h 1.2: 0 °C 2.1: trifluoroacetic anhydride / tetrahydrofuran / 1 h / -78 °C 2.2: 60.33 h / -78 °C / Reflux 2.3: 2 h / 20 °C 3.1: 10 palladium on activated charcoal; hydrogen / ethanol / -78 °C / 760.05 Torr 3.2: 60.33 h / -78 °C / Reflux 3.3: 2 h / 20 °C 4.1: sodium hydrogencarbonate / ethanol View Scheme