2-(4-氯苯氧基)-1-哌嗪-1-乙酮合成路线 （共 6 条）
反应条件
trifluoroacetic acid in dichloromethane T=20°C; Inert atmosphere;
参考文献
Journal of Medicinal Chemistry, , vol. 54, # 2 p. 655 - 668
反应条件
1: (4-chlorophenoxy)-acetic acid With N-bromosuccinmide; triphenylphosphine in dichloromethane T=0 - 5°C; 0.25 h; 2: piperazine With pyridine in dichloromethane T=20°C; 0.75 h;
参考文献
Synthetic Communications, , vol. 34, # 16 p. 2917 - 2924
反应条件
1: triethylamine / dichloromethane / 20 °C 2: trifluoroacetic acid / dichloromethane / 20 °C / Inert atmosphere View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 54, # 2 p. 655 - 668
反应条件
1: thionyl chloride / 8 h / Heating 2: 4N NaOH / H2O / 0.75 h View Scheme
参考文献
Journal of the Indian Chemical Society, , vol. 69, # 1 p. 45 - 46
反应条件
1: ethyl acetate 2: thionyl chloride / 8 h / Heating 3: 4N NaOH / H2O / 0.75 h View Scheme
参考文献
Journal of the Indian Chemical Society, , vol. 69, # 1 p. 45 - 46
反应条件
sodium hydroxide in water 0.75 h;
参考文献
Journal of the Indian Chemical Society, , vol. 69, # 1 p. 45 - 46
