N-叔丁氧羰基-L-吲哚啉-2-甲酸合成路线 （共 10 条）
反应条件
sodium hydroxide in 1,4-dioxane T=20°C; 12 h;
参考文献
Charton, Julie; Gassiot, Amaury Cazenave; Girault-Mizzi, Sophie; Debreu-Fontaine, Marie-Ange; Melnyk, Patricia; Sergheraert, Christian
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 21 p. 4833 - 4837
反应条件
Chirazyme L-2 in phosphate buffer T=60°C; pH=7.0; 30 h;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 77, # 5 p. 1021 - 1025
反应条件
1.1: HCl; NaNO2 / H2O / 0.25 h / 0 °C 1.2: 63 percent / KOH / ethanol; H2O / 15 h / 0 - 4 °C / pH 6.0 2.1: 732 mg / acetic acid / H2O / 15 h / 20 °C 3.1: 85 percent / HBr / acetic acid / 2 h / 20 °C 4.1: DBU / 3 h / Heating 5.1: 99 percent / 4-dimethylaminopyridine / tetrahydrofuran / 1 h / 20 °C 6.1: 92 percent / magnesium; methanol / 4 h / 0 °C 7.1: 49 percent / Chirazyme L-2 / aq. phosphate buffer / 30 h / 60 °C / pH 7.0 View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 77, # 5 p. 1021 - 1025
反应条件
1: 99 percent / 4-dimethylaminopyridine / tetrahydrofuran / 1 h / 20 °C 2: 92 percent / magnesium; methanol / 4 h / 0 °C 3: 49 percent / Chirazyme L-2 / aq. phosphate buffer / 30 h / 60 °C / pH 7.0 View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 77, # 5 p. 1021 - 1025
反应条件
1: 99 percent / 4-dimethylaminopyridine / tetrahydrofuran / 1 h / 20 °C 2: 92 percent / magnesium; methanol / 4 h / 0 °C 3: 49 percent / Chirazyme L-2 / aq. phosphate buffer / 30 h / 60 °C / pH 7.0 View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 77, # 5 p. 1021 - 1025
反应条件
1: DBU / 3 h / Heating 2: 99 percent / 4-dimethylaminopyridine / tetrahydrofuran / 1 h / 20 °C 3: 92 percent / magnesium; methanol / 4 h / 0 °C 4: 49 percent / Chirazyme L-2 / aq. phosphate buffer / 30 h / 60 °C / pH 7.0 View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 77, # 5 p. 1021 - 1025
反应条件
1: 80 percent / HBr / acetic acid / 2 h / 20 °C 2: 99 percent / 4-dimethylaminopyridine / tetrahydrofuran / 1 h / 20 °C 3: 92 percent / magnesium; methanol / 4 h / 0 °C 4: 49 percent / Chirazyme L-2 / aq. phosphate buffer / 30 h / 60 °C / pH 7.0 View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 77, # 5 p. 1021 - 1025
反应条件
1: 69 percent / 40 h / 20 °C 2: 49 percent / Chirazyme L-2 / aq. phosphate buffer / 30 h / 60 °C / pH 7.0 View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 77, # 5 p. 1021 - 1025
反应条件
1: 92 percent / magnesium; methanol / 4 h / 0 °C 2: 49 percent / Chirazyme L-2 / aq. phosphate buffer / 30 h / 60 °C / pH 7.0 View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 77, # 5 p. 1021 - 1025
反应条件
1: 85 percent / HBr / acetic acid / 2 h / 20 °C 2: DBU / 3 h / Heating 3: 99 percent / 4-dimethylaminopyridine / tetrahydrofuran / 1 h / 20 °C 4: 92 percent / magnesium; methanol / 4 h / 0 °C 5: 49 percent / Chirazyme L-2 / aq. phosphate buffer / 30 h / 60 °C / pH 7.0 View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 77, # 5 p. 1021 - 1025
