5-(溴甲基)-3-甲氧基异噁唑合成路线 （共 3 条）
反应条件
carbon tetrabromide; triphenylphosphine in dichloromethane T=0°C; 2 h;
参考文献
SYNGENTA LIMITED
Patent: WO2006/24820 A1, 2006 ;
Location in patent: Page/Page column 122 ;
反应条件
N-bromosuccinmide; meta-chloroperoxybenzoic acid in tetrachloromethane 24 h; Heating;
参考文献
Pajouhesh, Hassan; Curry, Kenneth
Tetrahedron Asymmetry, 1998 , vol. 9, # 16 p. 2757 - 2760
反应条件
1: Et3N / tetrahydrofuran / 1.25 h / 0 °C 2: NaBH4 / H2O / Ambient temperature 3: 80 percent / Ph3P, Br2, pyridine / CH2Cl2 / 0 °C View Scheme
参考文献
Ornstein; Arnold; Allen; Bleisch; Borromeo; Lugar; Leander; Lodge; Schoepp
Journal of Medicinal Chemistry, 1996 , vol. 39, # 11 p. 2232 - 2244
