6,7-二氟-1,4-二氢-8-甲基-4-氧代喹啉-3-羧酸合成路线 （共 4 条）
反应条件
sodium hydroxide in ethanol 6.5 h; Heating;
参考文献
Carretero; Garcia Ruano; Vicioso
Tetrahedron, 1992 , vol. 48, # 35 p. 7373 - 7382
反应条件
1: 75 percent / 1.5 h / 110 °C / Heating 2: 60 percent / diphenyl ether / 6 h / 220 °C 3: 90 percent / 2M NaOH / ethanol / 6.5 h / Heating View Scheme
参考文献
Carretero; Garcia Ruano; Vicioso
Tetrahedron, 1992 , vol. 48, # 35 p. 7373 - 7382
反应条件
1: 80 percent / conc. HCl / diethyl ether / 0.67 h / Ambient temperature 2: 75 percent / 1.5 h / 110 °C / Heating 3: 60 percent / diphenyl ether / 6 h / 220 °C 4: 90 percent / 2M NaOH / ethanol / 6.5 h / Heating View Scheme
参考文献
Carretero; Garcia Ruano; Vicioso
Tetrahedron, 1992 , vol. 48, # 35 p. 7373 - 7382
反应条件
1: 60 percent / diphenyl ether / 6 h / 220 °C 2: 90 percent / 2M NaOH / ethanol / 6.5 h / Heating View Scheme
参考文献
Carretero; Garcia Ruano; Vicioso
Tetrahedron, 1992 , vol. 48, # 35 p. 7373 - 7382
