2-氯-4-硝基吡啶 N-氧化物合成路线 （共 29 条）
参考文献
Alker, David; Ollis, W. David; Shahriari-Zavareh, Hooshang
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , # 6 p. 1623 - 1630
反应条件
1: With urea hydrogen peroxide addition compound; trifluoroacetic acid in dichloromethane T=0 - 20°C; 72 h; 2: With sodium dithionite in dichloromethane; water 0.25 h; 3: With hydrogenchloride in dichloromethane; water
参考文献
CHEMIZON (BEIJING), LTD.; XIAO, Dengming; ZHU, Li; WANG, Shixin; LIANG, Zhi; HU, Wei
Patent: WO2010/145197 A1, 2010 ;
Location in patent: Page/Page column 79-80 ;
WO 2010/145197 A1
反应条件
sulfuric acid; nitric acid T=90 - 100°C; 2.5 h;
参考文献
Kureha Kagaku Kogyo Kabushiki Kaisha
Patent: US6339045 B1, 2002 ;
Location in patent: Referential example 2 ;
反应条件
1: 91 percent / aq. H2O2 / trifluoroacetic acid / 4 h 2: 72 percent / aq. HNO3, H2SO4 / 2 h View Scheme
参考文献
Tetrahedron, , vol. 55, # 41 p. 11985 - 11996
反应条件
sulfuric acid; nitric acid
反应条件
1: concentrated sulfuric acid; peroxomonosulfuric acid 3: concentrated sulfuric acid; nitric acid View Scheme
参考文献
Journal of the American Chemical Society, , vol. 79, p. 3565
反应条件
2: concentrated sulfuric acid; nitric acid View Scheme
参考文献
Journal of the American Chemical Society, , vol. 79, p. 3565
反应条件
1: acetic acid; iron-powder / anschliessend mit Zink-Pulver unter Zusatz von wenig wss. HgCl2 2: NaNO2; aqueous H2SO4; CuSO4 / Diazotization.weitere Reagentien: Kupfer-Pulver, wss. Na2CO3 View Scheme
参考文献
Talik; Plazek
Roczniki Chemii, 1955 , vol. 29, p. 1019,1025
Chem.Abstr., 1956 , p. 12045
反应条件
1: 95 percent / iron powder, aq. HCl / ethanol / 3 h / Heating 2: 96 percent / NaOH / ethanol / 15 h / 170 °C View Scheme
参考文献
Tetrahedron, , vol. 55, # 41 p. 11985 - 11996
反应条件
1: NH3 / ethanol 3: PCl3 / CHCl3 4: H2O, HCl View Scheme
参考文献
MILLENNIUM PHARMACEUTICALS, INC.; GOULD, Alexandra, E.; HARRISON, Sean, J.
Patent: WO2011/146591 A1, 2011 ;
WO 2011/146591 A1
