2-甲基-6-亚甲基-2,7-辛二烯-4-醇合成路线 （共 26 条）
反应条件
1: NaHCO3 / toluene / 1.5 h / Heating
2: 68 percent / AcOH, toluene-p-sulphonic acid / diethyl ether; H2O / 1 h / 0 °C
3: 83 percent / 10percent KOH / ethanol; H2O / 3 h / 20 °C
View Scheme
参考文献
Masaki, Yukio; Hashimoto, Kinji; Sakuma, Kazuhiko; Kaji,Kenji
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , p. 1289 - 1295
反应条件
1: aq. AgNO3
2: NaBH4
View Scheme
参考文献
Reece,C.A. et al.
Tetrahedron, 1968 , vol. 24, p. 4249 - 4256
反应条件
alkaline hydrogen peroxide
1) ether, -78 deg C; Yield given. Multistep reaction;
参考文献
Brown, Herbert C.; Randad, Ramnarayan S.
Tetrahedron, 1990 , vol. 46, # 13-14 p. 4463 - 4472
反应条件
n-butyllithium; potassium tert-butylate; diisopropylamine
1.) THF/hexane, -70 deg C, 5 min 2.) THF/hexane; Yield given. Multistep reaction;
参考文献
Klusener, P. A. A.; Tip, L.; Brandsma, L.
Tetrahedron, 1991 , vol. 47, # 10/11 p. 2041 - 2064
反应条件
(i) Mg, Et2O, THF, (ii) /BRN= 2069980/; Multistep reaction;
参考文献
Karlsen; Froyen; Skattebol
Acta Chemica Scandinavica, 1976 , vol. 30, # 7 B p. 664 - 668
反应条件
nicotinamide adenine dinucleotide; recombinant Ipi12D04
pH=7.8; buffer (NaP and EDTA)Enzymatic reaction;
参考文献
Tittiger, Claus; Figueroa-Teran, Rubi; Blomquist, Gary J.
Patent: US2012/107265 A1, 2012 ;
Location in patent: Page/Page column 1; 2; 4; 5 ;
