(R)-1-溴-2,3-二羟基丙烷合成路线 （共 12 条）
反应条件
[(R,R)-N,N'-bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminato(2-)]cobalt(III) acetate; water in tetrahydrofuran T=4°C; 48 h;
参考文献
Schaus, Scott E.; Brandes, Bridget D.; Larrow, Jay F.; Tokunaga, Makoto; Hansen, Karl B.; Gould, Alexandra E.; Furrow, Michael E.; Jacobsen, Eric N.
Journal of the American Chemical Society, 2002 , vol. 124, # 7 p. 1307 - 1315
反应条件
[(R,R)-N,N'-bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminato(2-)]cobalt(III) acetate; water in tetrahydrofuran T=0°C;
参考文献
Schaus, Scott E.; Brandes, Bridget D.; Larrow, Jay F.; Tokunaga, Makoto; Hansen, Karl B.; Gould, Alexandra E.; Furrow, Michael E.; Jacobsen, Eric N.
Journal of the American Chemical Society, 2002 , vol. 124, # 7 p. 1307 - 1315
反应条件
lithium bromide in tetrahydrofuran; dichloromethane; ethyl acetate
参考文献
Nguyen-Ba; Nghe; Quimpere; Miguel; Kong; Laval Chan Chung; Brown; William L.; Dionne; Gervais
Patent: US5789394 A1, 1998 ;
反应条件
hydrogen bromide; sodium bromide; sodium nitrite in water T=10 - 20°C; Substitution; 20 h;
参考文献
Wang, Guijun; Hollingsworth, Rawle I.
Journal of Organic Chemistry, 1999 , vol. 64, # 3 p. 1036 - 1038
反应条件
[(R,R)-N,N-bis-(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamino-Co(III)-acetate]; water in tetrahydrofuran T=4°C; 24 h;
参考文献
Furrow, Michael E.; Schaus, Scott E.; Jacobsen, Eric N.
Journal of Organic Chemistry, 1998 , vol. 63, # 20 p. 6776 - 6777
反应条件
water; Cr(III)-endo,endo-2,5-diaminonorbornane-salen in tetrahydrofuran T=20°C; 22 h; Title compound not separated from byproducts;
参考文献
Solodenko, Wladimir; Jas, Gerhard; Kunz, Ulrich; Kirschning, Andreas
Synthesis, 2007 , # 4 p. 583 - 589
反应条件
lithium bromide; niobium bromide in tetrahydrofuran T=0°C;
参考文献
Nguyen-Ba, Paul; Lee, Nola; Mitchell, Helen; Chan, Laval; Quimpere, Miguel
Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 24 p. 3555 - 3560
反应条件
polystyrene-bound (R,R)-N-(3,5-di-t-butyl-6-hydroxy)benzylidene-N'-(3-t-butyl-2,5-dihydroxy)benzylidene-1,2-cyclohexanediamine; water in tetrahydrofuran 24 h; Ambient temperature; Yield given;
参考文献
Annis, D. Allen; Jacobsen, Eric N.
Journal of the American Chemical Society, 1999 , vol. 121, # 17 p. 4147 - 4154
反应条件
osmium(VIII) oxide; 2,5-diphenyl-4,6-diquinine-pyrimidine-ethylene glycol dimethacrylate -polymer T=20°C; 20 h; Product distribution;
参考文献
Becker, Heinrich; Sharpless, K. Barry
Angewandte Chemie, 1996 , vol. 108, # 4 p. 447 - 449
反应条件
aluminum oxide; N-bromosuccinmide; hydrogen; boric acid; palladium on activated charcoal 1.) dioxan, H2O, RT, 18 h; 2.) EtOH, RT, 3 h; Yield given. Multistep reaction. Title compound not separated from byproducts;
参考文献
Mueller, H. K.; Burgold, J.
Tetrahedron, 1986 , vol. 42, # 5 p. 1533 - 1538
