(S)-(-)-1-苯基乙醇合成路线 （共 393 条）
反应条件
1: acetyl chloride With 1,4-diaza-bicyclo[2.2.2]octane; (S)-3,3'-bis-(2,4,6-triisopropylphenyl)-BINOL phosphoric acid in diethyl ether T=20°C; 0.0833333 h; Inert atmosphereResolution of racemate; 2: sec-phenethyl alcohol in diethyl ether T=-20°C; 5 h; Resolution of racemateInert atmosphere; optical yield given as percent ee;
参考文献
Organic Letters, , vol. 14, # 13 p. 3486 - 3489
反应条件
in benzene T=21°C; 8 h; lipase Amano P/Celite 577; Yields of byproduct given;
参考文献
Bianchi, Daniele; Cesti, Pietro; Battistel, Ezio
Journal of Organic Chemistry, 1988 , vol. 53, # 23 p. 5531 - 5534
反应条件
in benzene T=25°C; 120 h; lipase Amano P/Celite 577; Yields of byproduct given;
参考文献
Bianchi, Daniele; Cesti, Pietro; Battistel, Ezio
Journal of Organic Chemistry, 1988 , vol. 53, # 23 p. 5531 - 5534
反应条件
sodium methylate in tetrahydrofuran T=0°C;
参考文献
Tetrahedron Letters, , vol. 27, # 1 p. 15 - 18
反应条件
in diethyl ether Yield given. Yields of byproduct given;
参考文献
Angewandte Chemie, , vol. 103, # 1 p. 100 - 101
反应条件
in benzene T=21°C; 2 h; lipase Amano P/Celite 577; Yields of byproduct given;
参考文献
Bianchi, Daniele; Cesti, Pietro; Battistel, Ezio
Journal of Organic Chemistry, 1988 , vol. 53, # 23 p. 5531 - 5534
反应条件
NaOH buffer; ethylenediaminetetraacetic acid; semisynthetic seleno-subtilisin; 3-mercapto-6-nitro-benzoic acid; citric acid T=25°C; 0.2 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Tetrahedron Asymmetry, , vol. 8, # 6 p. 853 - 856
反应条件
(S)-MeAl(OC6H(CH3)2(C6HCH3)2)2 in diethyl ether; dichloromethane T=-78°C; other reagent; Product distribution;
参考文献
Journal of Organic Chemistry, , vol. 62, # 16 p. 5651 - 5656
反应条件
50 U aminoacylase E.C. 3.5.1.14 in hexane T=20°C; Acylation; 48 h;
参考文献
Tetrahedron Asymmetry, , vol. 11, # 8 p. 1801 - 1808
反应条件
50 U aminoacylase E.C. 3.5.1.14 in hexane T=20°C; Acylation; 31.2 h;
参考文献
Tetrahedron Asymmetry, , vol. 11, # 8 p. 1801 - 1808
