(S)-(-)-1-苯基乙醇合成路线 （共 393 条）
反应条件
50 U aminoacylase E.C. 3.5.1.14 in hexane T=20°C; Acylation; 144 h;
参考文献
Tetrahedron Asymmetry, , vol. 11, # 8 p. 1801 - 1808
反应条件
50 U aminoacylase E.C. 3.5.1.14 in hexane T=20°C; Acylation; 168 h;
参考文献
Tetrahedron Asymmetry, , vol. 11, # 8 p. 1801 - 1808
反应条件
3 A molecular sieve; Humicola insolens ferulic acid esterase T=45°C; 72 h;
参考文献
Bioorganic Chemistry, , vol. 33, # 4 p. 325 - 337
反应条件
1: dinaphtho[2,1-a;1',2'-c]-1-phenyl-1,3,2-dioxaborepin With n-butyllithium; dichloromethane in tetrahydrofuran; hexane T=-100°C; 2: methyllithium in tetrahydrofuran; diethyl ether T=-78 - 20°C; 3: With sodium hydroxide; NaBO3 16 h;
参考文献
Journal of Organometallic Chemistry, , vol. 657, # 1-2 p. 136 - 145
反应条件
1: 1 percent Chromat. / Geotrichum candidum IFO 4597 cells on BL-100 polymer; cyclohexanone / hexane / 24 h / 30 °C 2: 71 percent / Geotrichum candidum IFO 4597 cells on BL-100 polymer; hexan-2-ol / hexane / 24 h / 30 °C 3: H2; NaOH / 5 percent Pd/C / ethanol / 20 °C View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 16 p. 2397 - 2402
反应条件
1: 71 percent / Geotrichum candidum IFO 4597 cells on BL-100 polymer; hexan-2-ol / hexane / 24 h / 30 °C 2: H2; NaOH / 5 percent Pd/C / ethanol / 20 °C View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 16 p. 2397 - 2402
反应条件
1: pyridine / 4 h / -10 °C 2: LiAlH4 / tetrahydrofuran / 3 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 26, # 1 p. 66 - 71
反应条件
1: BH3*THF / tetrahydrofuran / 5 h / Ambient temperature 2: pyridine / 4 h / -10 °C 3: LiAlH4 / tetrahydrofuran / 3 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 26, # 1 p. 66 - 71
反应条件
2: 30 percent / H2 / Raney Ni / methanol / 12 h / 0 °C View Scheme
参考文献
Chemische Berichte, , vol. 117, # 1 p. 413 - 414
反应条件
1: 12 h / 80 °C 2: 1.) sec-butyllithium / 1.) THF, 2.) ether 3: 91 percent / H2O2, KF, KHCO3 / 15 h / Ambient temperature View Scheme
参考文献
Journal of the American Chemical Society, , vol. 111, # 23 p. 8737 - 8738
