(S)-(-)-1-苯基乙醇合成路线 （共 393 条）
反应条件
Rhizopus nigricans (sterile potato dextrose medium) in tetrahydrofuran 16 h; Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Ziffer, Herman; Kawai, Ken-ichi; Kasai, Masaji; Imuta, Mitsuru; Froussios, Cleanthis
Journal of Organic Chemistry, 1983 , vol. 48, # 18 p. 3017 - 3021
反应条件
lithium triethylborohydride in tetrahydrofuran
参考文献
Journal of Organic Chemistry, , vol. 48, # 10 p. 1784 - 1786
反应条件
n-butyllithium; (2S,2'S)-2-hydroxymethyl-1-lt;(1-methylpyrrolidine-2-yl)methylgt;pyrrolidine investigation of the asymmetric addition of alkyllithium to an aldehyde in presence (2S,2S')-2-hydroxymethyl-1-<(1-methylpyrrolidine-2-yl)methyl>pyrrolidine; Product distributionMechanism;
参考文献
Tetrahedron, , vol. 37, # 23 p. 4111 - 4119
反应条件
potassium hydroxide in tetrahydrofuran; methanol 15 h; Ambient temperature;
参考文献
Tetrahedron, , vol. 45, # 2 p. 507 - 516
反应条件
polymer-bound TADDOL in toluene T=-75 - 0°C; 16 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Helvetica Chimica Acta, , vol. 79, # 6 p. 1710 - 1740
反应条件
Aspergillus niger biotransformation by diverse microorganisms, conversion percent, enantiomeric excess; Product distribution;
参考文献
Journal of Organic Chemistry, , vol. 63, # 22 p. 7598 - 7599
反应条件
50 U aminoacylase E.C. 3.5.1.14 in hexane T=20°C; Acylation; 168 h; Title compound not separated from byproducts;
参考文献
Tetrahedron Asymmetry, , vol. 11, # 8 p. 1801 - 1808
反应条件
1: trimethylaluminum With titanium(IV) isopropylate; (S)-2-hydroxy-3-phenylpropionic acid in tetrahydrofuran; toluene T=22°C; 2.5 h; 2: benzaldehyde in tetrahydrofuran; toluene T=22°C; 2.5 h; Title compound not separated from byproducts;
参考文献
Tetrahedron Asymmetry, , vol. 16, # 4 p. 851 - 855
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene; 1,3-di[(S)-1-phenylethyl]benzimidazolium iodide; phenol in toluene
参考文献
Organic Letters, , vol. 7, # 5 p. 905 - 908
反应条件
1: 1.) oxalyl chloride/DMSO; 2.) Et3N / CH2Cl2 / 1.) -78 deg C, 17 min; 2.) a.) -78 deg C, 5 min; b.) RT, 30 min 2: K2CO3 / methanol / 12 h / Ambient temperature View Scheme
参考文献
Journal of Organometallic Chemistry, , vol. 285, p. 83 - 94
