(S)-(-)-1-苯基乙醇合成路线 （共 393 条）
反应条件
1: immobilized CALB lipase; ammonia / di-isopropyl ether / 7 h / 35 °C / Enzymatic reaction 2: Escherichia coli BioH esterase immobilized on Macroporous adsorptive resin / 25 h / 35 °C / Enzymatic reaction View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 22, # 9 p. 980 - 985
反应条件
1.1: sodium tetrahydroborate / methanol / 0.5 h / 20 °C 1.2: 0.17 h / 20 °C / Saturated solution 2.1: Escherichia coli BioH esterase immobilized on Macroporous adsorptive resin / 25 h / 35 °C / Enzymatic reaction View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 22, # 9 p. 980 - 985
反应条件
1: formic acid; triethylamine / ethyl acetate / 24 h / 25 °C / Inert atmosphere 2: Candida antarctica lipase B / Resolution of racemate; Enzymatic reaction View Scheme
参考文献
Chemistry - A European Journal, , vol. 18, # 24 p. 7394 - 7403
反应条件
hydrogenchloride; water in dichloromethane Inert atmosphere;
参考文献
Chemical Communications, , vol. 49, # 43 p. 4893 - 4895
反应条件
hydrogenchloride; water in dichloromethane Inert atmosphere;
参考文献
Chemical Communications, , vol. 49, # 43 p. 4893 - 4895
参考文献
Journal of Organic Chemistry, , vol. 53, # 23 p. 5531 - 5534
反应条件
potassium fluoride; dihydrogen peroxide; potassium hydrogencarbonate 1) THF, MeOH, 2) THF, MeOH, 60 deg C, 15 h; Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 56, # 25 p. 7076 - 7083
反应条件
alkaline H2O2; lithium triethylborohydride 1.) THF, RT, overnight; Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 50, # 9 p. 1384 - 1394
反应条件
nickel Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 47, # 7 p. 1196 - 1200
反应条件
2BH3*NH2CH2CH2NH2 in solid enantioselective reduction of var. ketones in optically active host compounds with a BH3-ethylenediamine complex in the solid state; Product distribution;
参考文献
Toda, Fumio; Mori, Koji
Journal of the Chemical Society, Chemical Communications, 1989 , # 17 p. 1245 - 1246
