(S)-(-)-1-苯基乙醇合成路线 (共 393 条)
反应条件
1: With Candida antarctica lipase B in tetrahydrofuran 16 h; Enzymatic reaction; 2: With hydrogenchloride; water in methanol optical yield given as percent ee;
参考文献
Organic Process Research and Development, , vol. 13, # 4 p. 706 - 709
反应条件
ethylbenzene dehydrogenase; water in aq. buffer pH=7.5; Inert atmosphereEnzymatic reaction; Kinetics;
参考文献
Angewandte Chemie - International Edition, , vol. 52, # 9 p. 2599 - 2601
Angew. Chem., , vol. 125, # 9 p. 2660 - 2662,3
反应条件
sodium hydroxide; sodium; acetic acid 1.) 0 deg C; 2.) THF, 20 deg C; Multistep reaction;
参考文献
Helvetica Chimica Acta, , vol. 64, # 7 p. 2485 - 2488
反应条件
N,N-bis-2-(hydroxyethyl)-2-amino ethane sulfonic acid; lipase from Ophiostoma piliferum in water T=25°C; pH=7.20; Enzyme kinetics;
参考文献
Tetrahedron Asymmetry, , vol. 12, # 4 p. 545 - 556
反应条件
Novozym 435; Al-beta (Si/Al 150) T=60°C;
参考文献
Chemistry - A European Journal, , vol. 13, # 2 p. 541 - 547
反应条件
Novozym 435; Al-beta (Si/Al 150) T=60°C;
参考文献
Chemistry - A European Journal, , vol. 13, # 2 p. 541 - 547
反应条件
1: Na2S 2: 1.) Na; 2.) AcOH, NaOH / 1.) 0 deg C; 2.) THF, 20 deg C View Scheme
参考文献
Helvetica Chimica Acta, , vol. 64, # 7 p. 2485 - 2488
反应条件
T=-35°C; optical yield given as percent ee;
参考文献
Journal of Organic Chemistry, , vol. 74, # 12 p. 4560 - 4564
反应条件
sulfuric acid; sodium nitrite
参考文献
Chemische Berichte, , vol. 45, p. 999
反应条件
T=4°C; chloroperoxidase from Caldariomyces fumago in citrate buffer as catalyst; Yield given. Yields of byproduct given;
参考文献
Journal of Organic Chemistry, , vol. 57, # 28 p. 7265 - 7270