(S)-(-)-1-苯基乙醇合成路线 (共 393 条)
反应条件
Sphingomonas paucimobilis NCIMB 8195 in water; N,N-dimethyl-formamide 168 h;
参考文献
Allan; Carnell
Journal of Organic Chemistry, 2001 , vol. 66, # 19 p. 6495 - 6497
反应条件
C48H48N2O4Ru2 in benzene T=30°C; 20 h; IrradiationDarkness; optical yield given as percent ee;
参考文献
Do, Youngshil; Hwang, In-Chul; Kim, Mahn-Joo; Park, Jaiwook
Journal of Organic Chemistry, 2010 , vol. 75, # 16 p. 5740 - 5742
反应条件
potassium tert-butylate; η5-Ph5CpRu(CO)2Cl in tetrahydrofuran; toluene T=20°C;
参考文献
Martin-Matute, Belen; Aberg, Jenny B.; Edin, Michaela; Baeckvall, Jan-E.
Chemistry - A European Journal, 2007 , vol. 13, # 21 p. 6063 - 6072
反应条件
hydroxide; triphenylphosphine; diethylazodicarboxylate 1.) THF, - 30 deg C; ee(S) : 68percent. Var. temp.; Multistep reaction. Title compound not separated from byproducts;
参考文献
Cabaret, Daniel; Maigrot, Nicole; Welvart, Zoltan
Tetrahedron Letters, 1981 , vol. 22, # 52 p. 5279 - 5282
反应条件
CS-180 in toluene T=60°C; Kinetics;
参考文献
Wang, Jie; Do, Dong-Minh; Chuah, Gaik-Khuan; Jaenicke, Stephan
ChemCatChem, 2013 , vol. 5, # 1 p. 247 - 254
反应条件
P=1E-06 Torr; Equilibrium constant;
参考文献
Fagin, Adelaide E.; Wang, Guoping; Lau, Michel C.; Gronert, Scott
Organic Letters, 2008 , vol. 10, # 9 p. 1771 - 1773
反应条件
alanine dehydrogenase; (S)-α-alanine; pyridoxal 5'-phosphate; nicotinamide adenine dinucleotide; ammonium chloride; alcohol dehydrogenase in aq. phosphate buffer T=30°C; 24 h; Enzymatic reaction;
参考文献
Tauber, Katharina; Fuchs, Michael; Sattler, Johann H.; Pitzer, Julia; Pressnitz, Desiree; Koszelewski, Dominik; Faber, Kurt; Pfeffer, Jan; Haas, Thomas; Kroutil, Wolfgang
Chemistry - A European Journal, 2013 , vol. 19, # 12 p. 4030 - 4035
反应条件
potassium tert-butylate; η5-Ph5CpRu(CO)2Cl in tetrahydrofuran; toluene T=80°C;
参考文献
Chemistry - A European Journal, , vol. 13, # 21 p. 6063 - 6072
反应条件
1: (S)-alpha-methylbenzyl alcohol With pyridine; phosphorus tribromide in diethyl ether T=-20 - 0°C; 2: sodium cyanide in N,N-dimethyl-formamide T=80°C; 3: With hydrogenchloride in dichloromethane Heating; Title compound not separated from byproducts;
参考文献
Thakur, Vinay V.; Sudalai
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2005 , vol. 44, # 3 p. 557 - 562
反应条件
silver hexafluoroantimonate; platinum (II) chloride in 1,2-dichloro-ethane T=50°C;
参考文献
Shibata, Takanori; Fujiwara, Ryo; Ueno, Yasunori
Synlett, 2005 , # 1 art. no. U26004ST, p. 152 - 154