(S)-(-)-1-苯基乙醇合成路线 （共 393 条）
反应条件
phosphite dehydrogenase; recombinant phenylacetone monooxygenase from Thermobifida fusca; NADPH in dimethyl sulfoxide T=30°C; pH=9; 3 h; Tris/HCl bufferEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Advanced Synthesis and Catalysis, , vol. 353, # 11-12 p. 2169 - 2173
反应条件
rabbit liver microsomal cytochrome P-450 in water T=25°C; 12 h;
参考文献
Journal of the American Chemical Society, , vol. 108, # 19 p. 6024 - 6031
反应条件
(S,S)-2,3-O-isopropylidene-1,1,4,4-tetraphenylthreitol in hexane T=20°C; 72 h;
参考文献
Vinogradov; Gorshkova; Chel'tsova; Kurilov; Ferapontov; Shishkin; Heise
Russian Chemical Bulletin, 2003 , vol. 52, # 8 p. 1841 - 1846
反应条件
1: With hydrogen; [Ru{(S)-MeO-BIPHEP}Br2] in methanol T=25°C; Hydrogenation; P=37503.8 Torr; 2: With nickel desulfurization; Further stages. Title compound not separated from byproducts.;
参考文献
European Journal of Organic Chemistry, , # 8 p. 1535 - 1537
反应条件
Escherichia coli BioH in hexane T=35°C; 28 h; Resolution of racemate; optical yield given as percent eeenantioselective reaction;
参考文献
Wang, Bo; Tang, Xiaoling; Liu, Ji; Yu, Hongwei
Tetrahedron Letters, 2010 , vol. 51, # 48 p. 6360 - 6364
反应条件
1: With aluminum isopropoxide in toluene T=70°C; P=142.514 Torr; 23 h; 2: With methanol; potassium hydroxide; water T=20°C; 0.5 h; Product distribution / selectivity;
参考文献
DSM IP ASSETS B.V.
Patent: WO2005/14509 A1, 2005 ;
Location in patent: Page/Page column 21 ;
反应条件
Candida antarctica lipase fraction B immobilized on acrylic resin in aq. phosphate buffer; diethyl ether T=20°C; pH=7; 48 h; Resolution of racemateEnzymatic reaction; enantioselective reaction;
参考文献
Tetrahedron Asymmetry, , vol. 24, # 5-6 p. 290 - 296
反应条件
N-benzyl-1,4-dihydronicotinamide; RhCl(PPh3)3 in acetonitrile
参考文献
Nakamura, Kaoru; Ushio, Kazutoshi; Oka, Shinzaburo; Ohno, Atsuyoshi; Yasui, Shinro
Tetrahedron Letters, 1984 , vol. 25, # 36 p. 3979 - 3982
反应条件
imidazolium alkyl-PEG sulfate ionic liquid coated lipase PS in di-isopropyl ether T=35°C; Enzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Green Chemistry, , vol. 12, # 11 p. 1976 - 1980
反应条件
potassium hydroxide; [Ir(μ-Cl)(1,5-cyclooctadiene)]2; polymer containing chiral cyclohexanediimine; styrene and divinylbenzene Ambient temperatureother polymers as ligands; Product distribution;
参考文献
Tetrahedron Asymmetry, , vol. 9, # 6 p. 897 - 900
