(S)-(-)-1-苯基乙醇合成路线 （共 393 条）
反应条件
5-chloro-4,9-(chlorobenzene-2,3-diyl)-2,4-dihydroxy-3a,4,9,9a-tetrahydro-1H-benzo[f]isoindole-1,3(2H)-dione; oxygen; anhydrous cobalt diacetate in acetonitrile T=60°C; P=760.051 Torr; enantioselective reaction;
参考文献
Shen, Juan; Tan, Choon-Hong
Organic and Biomolecular Chemistry, 2008 , vol. 6, # 22 p. 4096 - 4098
反应条件
perchloric acid in various solvent(s) T=64.5°C; other acid; Rate constantMechanism;
参考文献
Journal of the American Chemical Society, , vol. 112, # 9 p. 3560 - 3566
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 5 h; Heating;
参考文献
Imuta, Mitsuru; Kawai, Ken-ichi; Ziffer, Herman
Journal of Organic Chemistry, 1980 , vol. 45, # 16 p. 3352 - 3355
反应条件
n-butyllithium; (2S,2'S)-2-hydroxymethyl-1-lt;(1-methylpyrrolidine-2-yl)methylgt;pyrrolidine in toluene T=-110°C; 1 h; Yield given. Yields of byproduct given;
参考文献
Tetrahedron, , vol. 37, # 23 p. 4111 - 4119
反应条件
sodium hypophosphite; Raney Ni(W-2) in ethanol; water 0.5 h; Ambient temperature;
参考文献
Node, Manabu; Nishide, Kiyoharu; Shigeta, Yukihiro; Obata, Kenichi; Shiraki, Hiroaki; Kunishige, Hideaki
Tetrahedron, 1997 , vol. 53, # 38 p. 12883 - 12894
344580-04-72,2,2-三氟乙基4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-十七氟十一烷酸酯
→
反应条件
Chirazyme L-2 in acetonitrile T=20°C; 19 h; Enzymatic reaction;
参考文献
Journal of Organic Chemistry, , vol. 67, # 6 p. 1781 - 1785
反应条件
Brassica rapa var. rapa peroxidase; 2-methoxy-phenol T=20°C; pH=6; 3.5 h; aq. phosphate bufferEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Tetrahedron Asymmetry, , vol. 23, # 8 p. 594 - 601
反应条件
sodium hypophosphite; Raney-Ni (W-2) in ethanol; water 0.5 h; Ambient temperaturepH=5.2;
参考文献
Node, Manabu; Nishide, Kiyoharu; Shigeta, Yukihiro; Obata, Kenichi; Shiraki, Hiroaki; Kunishige, Hideaki
Tetrahedron, 1997 , vol. 53, # 38 p. 12883 - 12894
反应条件
sodium hypophosphite; Raney-Ni (W-2) in ethanol; water 0.5 h; Ambient temperaturepH=5.2;
参考文献
Node, Manabu; Nishide, Kiyoharu; Shigeta, Yukihiro; Obata, Kenichi; Shiraki, Hiroaki; Kunishige, Hideaki
Tetrahedron, 1997 , vol. 53, # 38 p. 12883 - 12894
反应条件
Candida antarctica lipase B immobilized on macroporous resin T=40°C; P=10 Torr; 8 h;
参考文献
Journal of Organic Chemistry, , vol. 66, # 5 p. 1906 - 1909
