(S)-(-)-1-苯基乙醇合成路线 （共 393 条）
反应条件
4 A molecular sieve; Lipase from Burkholderia cepacia in 1,4-dioxane T=30°C; 48 h;
参考文献
Journal of the American Chemical Society, , vol. 127, # 35 p. 12228 - 12229
反应条件
N-ethyl-N,N-diisopropylamine; CF3-PIP in chloroform T=0°C; 6 - 8.25 h; Resolution of racemate; Product distribution / selectivity;
参考文献
US2005/256150 A1, ;
Page/Page column 15; 16; 18; 19-20 ;
反应条件
Novozym 435(R); 1-n-butyl-3-methylimidazolium hexafluorophosphate T=35°C; P=100 Torr; 96 h; Title compound not separated from byproducts.;
参考文献
Angewandte Chemie - International Edition, , vol. 46, # 43 p. 8178 - 8181
反应条件
(R)-(+)-N-methylbenzoguanidine; trimethylacetic anhydride in diethyl ether T=20°C; 12 h; Resolution of racemate; optical yield given as percent ee;
参考文献
Organic and Biomolecular Chemistry, , vol. 9, # 20 p. 7092 - 7096
反应条件
lipase B from Candida antarctica in cyclohexane T=50°C; 0.75 h; Resolution of racemate; optical yield given as percent ee;
参考文献
Li, Xiang; Shi, Yi; Wang, Zhoujun; Zhang, Yahong; Tang, Yi
Journal of Catalysis, 2012 , vol. 288, p. 24 - 32
反应条件
hydrogen cation in water Yield given;
参考文献
Chemische Berichte, , vol. 117, # 4 p. 1330 - 1354
反应条件
sodium hydroxide in methanol 6 h; RefluxInert atmosphere;
参考文献
Maywald, Matthias; Pfaltz, Andreas
Synthesis, 2009 , # 21 p. 3654 - 3660
反应条件
2,2'-azo-bisisobutyronitrile; triphenylstannane in benzene Reduction; Heating;
参考文献
Tiecco, Marcello; Testaferri, Lorenzo; Bagnoli, Luana; Marini, Francesca; Temperini, Andrea; Tomassini, Cristina; Santi, Claudio
Tetrahedron Letters, 2000 , vol. 41, # 17 p. 3241 - 3245
反应条件
Candida antarctica lipase B in diethyl ether T=20°C; 30 h; Enzymatic reaction; optical yield given as percent ee;
参考文献
Tetrahedron Asymmetry, , vol. 20, # 10 p. 1191 - 1196
反应条件
1: acetophenone With aluminum oxide; sodium tetrahydroborate in hexane T=40°C; 3 h; 2: 2-acetyloxy-1-propene With Lipase 'Amano' PS-C II in hexane T=25°C; 4 h;
参考文献
Tetrahedron Asymmetry, , vol. 13, # 8 p. 815 - 820
