N-cbz-dl-丝氨酸甲酯合成路线 （共 11 条）
反应条件
sodium carbonate in tetrahydrofuran T=20°C; 12 h;
参考文献
Roux, Lionel; Charrier, Cedric; Salomon, Emmanuel; Ilhan, Meral; Bisseret, Philippe; Tarnus, Celine
Tetrahedron Letters, 2011 , vol. 52, # 20 p. 2586 - 2589
反应条件
thionyl chloride T=-20 - 20°C;
参考文献
LEAD THERAPEUTICS, INC.
Patent: US2009/62268 A1, 2009 ;
Location in patent: Page/Page column 45 ;
US 20090062268 A1
反应条件
in tetrahydrofuran; methanol T=22°C; 0.416667 h;
参考文献
Journal of the American Chemical Society, , vol. 107, # 24 p. 7105 - 7109
反应条件
indium(III) chloride in water; acetonitrile 3 h; Heating;
参考文献
Yadav; Subba Reddy; Madan
New Journal of Chemistry, 2000 , vol. 24, # 11 p. 853 - 854
反应条件
1: 60 percent / Ph3P, dimethyl azodicarboxylate / tetrahydrofuran / 2.5 h / 20 °C 2: 88 percent / methanol; tetrahydrofuran / 0.42 h / 22 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 107, # 24 p. 7105 - 7109
参考文献
Loudwig, Sandra; Goeldner, Maurice
Tetrahedron Letters, 2001 , vol. 42, # 45 p. 7957 - 7959
反应条件
chloroform; magnesium oxide; benzyl chloroformate Reagens 4: H2O;
参考文献
Acta Chemica Scandinavica (1947-1973), , vol. 12, p. 561,565
反应条件
methanol; diethyl ether
参考文献
Monatshefte fuer Chemie, , vol. 85, p. 607,610,622
反应条件
2: (saponification) View Scheme
参考文献
Callahan,F.M. et al.
Journal of the American Chemical Society, 1963 , vol. 85, p. 201 - 207
反应条件
sodium tetrahydroborate; lithium chloride in tetrahydrofuran; ethanol 18 h; Ambient temperature;
参考文献
Harada, Hiroshi; Morie, Toshiya; Hirokawa, Yoshimi; Kato, Shiro
Chemical and Pharmaceutical Bulletin, 1996 , vol. 44, # 12 p. 2205 - 2212
