反应条件
1: glacial CH3COOH / 1.5 h / Heating 2: 5.46 g / aq. NaOH / methanol / 2 h / Heating 3: 5.86 g / polyphosphoric acid / 20 h / 150 °C 4: 1.) t-BuOK / 1.) DMSO, RT, 30 min, 2.) DMSO, 14 h 5: CF3COOH / CH2Cl2 / 24 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 36, # 25 p. 4040 - 4051
