2-氧代-6-(三氟甲基)-1,2-二氢吡啶-3-羧酸甲酯合成路线 (共 4 条)
反应条件
methanol; sodium 18 h; Heating / reflux;
参考文献
Ziemer, Frank; Willms, Lothar; Rosinger, Christopher; Auler, Thomas; Hacker, Erwin; Bickers, Udo
Patent: US2008/269059 A1, 2008 ;
Location in patent: Page/Page column 19 ;
反应条件
sodium methylate in methanol
参考文献
E. I. Du Pont de Nemours and Company
Patent: US5393734 A1, 1995 ;
反应条件
triethylamine T=20°C; Cooling with ice;
参考文献
SOLVAY SA; BRAUN, Max
Patent: WO2010/37688 A1, 2010 ;
Location in patent: Page/Page column 9 ;
反应条件
in N-methyl-acetamide; dichloromethane; ethyl acetate
参考文献
E. I. Du Pont de Nemours and Company
Patent: US5393734 A1, 1995 ;