2-溴-6-(三氟甲基)烟酸甲酯合成路线 （共 3 条）
反应条件
hydrogen bromide in acetic acid T=20°C; 3.5 h;
参考文献
WO2008/6540 A1, ;
Page/Page column 55 ;
反应条件
in N-methyl-acetamide; dichloromethane; ethyl acetate
参考文献
E. I. Du Pont de Nemours and Company
Patent: US5393734 A1, 1995 ;
反应条件
1: With diisobutylaluminium hydride in tetrahydrofuran T=-78 - 25°C; 2 h; 2: With water; citric acid in tetrahydrofuran; ethyl acetate
参考文献
PFIZER PRODUCTS INC.
Patent: WO2006/56854 A1, 2006 ;
Location in patent: Page/Page column 58; 59 ;
