(3R)-3-羟基-4-(三苯基甲氧基)-丁酸甲酯合成路线 (共 3 条)
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine in N,N-dimethyl-formamide 12 h; Ambient temperature;
参考文献
Thiam; Slassi; Chastrette; Amouroux
Synthetic Communications, 1992 , vol. 22, # 1 p. 83 - 95
反应条件
in pyridine; dichloromethane; ethyl acetate
参考文献
Sandoz Pharm. Corp.
Patent: US4870199 A1, 1989 ;
反应条件
1: NaBH4, BH3-Me2S 2: 90 percent / Et3N, dimethylaminopyridine / dimethylformamide / 12 h / Ambient temperature View Scheme
参考文献
Prasad, Kapa; Chen, Kau-Ming; Repic, Oljan; Hardtmann, Goetz E.
Tetrahedron: Asymmetry, 1990 , vol. 1, # 5 p. 307 - 310