5-[[4-[2-(5-乙基-2-吡啶基)-乙氧基]苯基]亚甲基]-2,4-噻唑烷二酮合成路线 （共 12 条）
反应条件
1: With sodium tetrahydroborate; Co(NO3)2⋅6H2O; dmgH2; sodium hydroxide in water; N,N-dimethyl-formamide T=35°C; 6 h; Large scale reaction; 2: With acetic acid in water; N,N-dimethyl-formamide T=25°C; pH=6.5 - 7; 0.75 h; Large scale reaction; 3: With hydrogenchloride in water; isopropyl alcohol T=25 - 80°C; Large scale reaction;
参考文献
Organic Process Research and Development, , vol. 13, # 6 p. 1190 - 1194
反应条件
1: With hydrogen; palladium 10 on activated carbon in formic acid T=75 - 80°C; P=6000.6 Torr; 6 h; 2: With sodium hydroxide in formic acid; water T=20°C; pH=3.25; 0.166667 h;
参考文献
PPG-SIPSY, PPG-SIPSY
Patent: JP2004/520401 A, 2004 ;
Location in patent: Page 6 ;
