1-[(苯基甲氧基)羰基]-L-脯氨酰-L-亮氨酰-甘氨酰胺合成路线 （共 13 条）
反应条件
triethylamine; proteinase K in acetonitrile T=30°C; 48 h;
参考文献
Cerovsky, Vaclav; Martinek, Karel
Collection of Czechoslovak Chemical Communications, 1989 , vol. 54, # 7 p. 2027 - 2041
反应条件
tetrahydrofuran; chloroformic acid ethyl ester; triethylamine anschliessend Behandeln mit einer wss. Loesung von N-L-Leucyl-glycin-amid vom pH 10;
参考文献
Ivanov, A. K.; Antonov, A. A.; Donetskii, I. A.
Chemistry of Natural Compounds, 1992 , vol. 28, # 3/4 p. 344 - 349
Khimiya Prirodnykh Soedinenii, 1992 , # 3,4 p. 393 - 400
反应条件
V8 protease in N,N-dimethyl-formamide T=37°C; pH=8.0;
参考文献
Wehofsky, Nicole; Koglin, Norman; Thust, Sven; Bordusa, Frank
Journal of the American Chemical Society, 2003 , vol. 125, # 20 p. 6126 - 6133
反应条件
ammonium hydroxide in N,N-dimethyl-formamide 0.25 h; Ambient temperature;
参考文献
Amblard, Muriel; Rodriguez, Marc; Martinez, Jean
Tetrahedron, 1988 , vol. 44, # 16 p. 5101 - 5108
反应条件
α-chymotrypsin in water; N,N-dimethyl-formamide T=38°C; 2 h; pH 7, CaCl2;
参考文献
Cerovsky; Jost
Collection of Czechoslovak Chemical Communications, 1985 , vol. 50, # 12 p. 2775 - 2782
反应条件
1: dimethylformamide; various solvent(s) / 37 °C / pH 8.0 2: V8 protease / dimethylformamide; various solvent(s) / 37 °C / pH 8.0 View Scheme
参考文献
Wehofsky, Nicole; Koglin, Norman; Thust, Sven; Bordusa, Frank
Journal of the American Chemical Society, 2003 , vol. 125, # 20 p. 6126 - 6133
参考文献
Zaoral; Rudinger
Collection of Czechoslovak Chemical Communications, 1955 , vol. 20, p. 1183,1185
Full Text Show Details
Bodanszky; du Vigneaud
Journal of the American Chemical Society, 1959 , vol. 81, p. 5688,5689, 5690
Biochemical Preparations, 1962 , vol. 9, p. 110,111 Anm. 2
反应条件
1: ethyl acetate; dicyclohexylcarbodiimide 2: triethylamine; CHCl3 3: HBr; acetic acid / Behandeln des Reaktionsprodukts in CHCl3 mit 1-Benzyloxycarbonyl-L-prolin und Triaethylamin 4: methanol; NH3 View Scheme
参考文献
Bodanszky; du Vigneaud
Journal of the American Chemical Society, 1959 , vol. 81, p. 5688,5689, 5690
Biochemical Preparations, 1962 , vol. 9, p. 110,111 Anm. 2
反应条件
1: triethylamine; CHCl3 2: HBr; acetic acid / Behandeln des Reaktionsprodukts in CHCl3 mit 1-Benzyloxycarbonyl-L-prolin und Triaethylamin 3: methanol; NH3 View Scheme
参考文献
Bodanszky; du Vigneaud
Journal of the American Chemical Society, 1959 , vol. 81, p. 5688,5689, 5690
Biochemical Preparations, 1962 , vol. 9, p. 110,111 Anm. 2
反应条件
1: HBr; acetic acid / Behandeln des Reaktionsprodukts in CHCl3 mit 1-Benzyloxycarbonyl-L-prolin und Triaethylamin 2: methanol; NH3 View Scheme
参考文献
Bodanszky; du Vigneaud
Journal of the American Chemical Society, 1959 , vol. 81, p. 5688,5689, 5690
Biochemical Preparations, 1962 , vol. 9, p. 110,111 Anm. 2
