2-羟基-5-甲基苯乙酮合成路线 （共 181 条）
反应条件
pyridine
T=50°C; Schotten-Baumann reaction; 0.5 h;
参考文献
Kahnberg, Pia; Lager, Erik; Rosenberg, Celia; Schougaard, Jette; Camet, Linda; Sterner, Olov; Nielsen, Elsebet stergaard; Nielsen, Mogens; Liljefors, Tommy
Journal of Medicinal Chemistry, 2002 , vol. 45, # 19 p. 4188 - 4201
反应条件
1: 87 percent / pyridine / 0.5 h / 50 °C
2: 76 percent / pyridine; KOH / 1.5 h / 50 °C
View Scheme
参考文献
Mazumdar; Karmakar; Rangachari; Banerjee; Banerji
Journal of the Indian Chemical Society, 1990 , vol. 67, # 11 p. 911 - 913
反应条件
1: 91 percent / pyridine / 0.5 h / 50 °C
2: 85 percent / pyridine; KOH / 1.5 h / 50 °C
View Scheme
参考文献
Kahnberg, Pia; Lager, Erik; Rosenberg, Celia; Schougaard, Jette; Camet, Linda; Sterner, Olov; Nielsen, Elsebet stergaard; Nielsen, Mogens; Liljefors, Tommy
Journal of Medicinal Chemistry, 2002 , vol. 45, # 19 p. 4188 - 4201
反应条件
1: 82 percent / pyridine / 0.5 h / 50 °C
2: 96 percent / pyridine; KOH / 1.5 h / 50 °C
View Scheme
参考文献
Adam, Waldemar; Golsch, Dieter; Hadjiarapoglou, Lazaros
Journal of Organic Chemistry, 1991 , vol. 56, # 26 p. 7292 - 7297
反应条件
1: 91 percent / pyridine / 0.5 h / 50 °C
2: 85 percent / pyridine; KOH / 1.5 h / 50 °C
3: 85 percent / conc. H2SO4 / acetic acid / 2 h / 80 °C
View Scheme
参考文献
Kahnberg, Pia; Lager, Erik; Rosenberg, Celia; Schougaard, Jette; Camet, Linda; Sterner, Olov; Nielsen, Elsebet stergaard; Nielsen, Mogens; Liljefors, Tommy
Journal of Medicinal Chemistry, 2002 , vol. 45, # 19 p. 4188 - 4201
反应条件
1: 82 percent / pyridine / 0.5 h / 50 °C
2: 96 percent / pyridine; KOH / 1.5 h / 50 °C
3: 91 percent / conc. H2SO4 / acetic acid / 2 h / 80 °C
View Scheme
参考文献
Adam, Waldemar; Golsch, Dieter; Hadjiarapoglou, Lazaros
Journal of Organic Chemistry, 1991 , vol. 56, # 26 p. 7292 - 7297
反应条件
1: amalgamated zinc, HCl
View Scheme
参考文献
Fischer, Alfred; Henderson, George N.
Canadian Journal of Chemistry, 1981 , vol. 59, p. 2314 - 2327
反应条件
aluminium trichloride in nitrobenzene
T=80°C; 8 h; Yield given;
参考文献
Mandal, Sanat Kumar; Nag, Kamalaksha
Journal of the Chemical Society, Dalton Transactions: Inorganic Chemistry (1972-1999), 1983 , p. 2429 - 2434
反应条件
1: pyridine / 0.25 h / 0 °C
2: AlCl3 / 2 h / 130 - 140 °C
View Scheme
参考文献
Kotali; Glaveri; Pavlidou; Tsoungas
Synthesis, 1990 , # 12 p. 1172 - 1173
反应条件
1: 87 percent / pyridine / 0.5 h / 50 °C
2: 76 percent / pyridine; KOH / 1.5 h / 50 °C
3: 96 percent / conc. H2SO4 / acetic acid / 2 h / 80 °C
View Scheme
参考文献
Mazumdar; Karmakar; Tiwari; Banerjee; Banerji
Journal of the Indian Chemical Society, 1990 , vol. 67, # 10 p. 845 - 847
