2-羟基-5-甲基苯乙酮合成路线 （共 181 条）
反应条件
1: Br2 / acetic acid; acetic acid / 1 h
2: CH3COONa / dimethylformamide / 1 h / Heating
View Scheme
参考文献
Deshpande, A.R.; Paradkar, M.V.
Synthetic Communications, 1990 , vol. 20, # 6 p. 809 - 816
参考文献
Marathe
Journal of the University of Poona, Science and Technology, 1958 , # 14 p. 63,66
反应条件
1: 62 percent / K2CO3; tetrabutylammonium bromide / benzene; H2O / 16 h / Heating
2: 80 percent / NaH / tetrahydrofuran / 80 h / 25 °C
View Scheme
参考文献
Nikitin, Kirill V.; Andryukhova, Nonna P.
Canadian Journal of Chemistry, 2004 , vol. 82, # 5 p. 571 - 578
参考文献
Das, Jhantu; Ghosh, Somnath
Tetrahedron Letters, 2011 , vol. 52, # 52 p. 7189 - 7194
反应条件
tert.-butylhydroperoxide; Cu(OAc)2*2H2O in decane
T=120°C; 4 h; chemoselective reaction;
参考文献
Rout, Saroj Kumar; Guin, Srimanta; Banerjee, Arghya; Khatun, Nilufa; Gogoi, Anupal; Patel, Bhisma K.
Organic Letters, 2013 , vol. 15, # 16 p. 4106 - 4109
反应条件
1: sodium hydride / tetrahydrofuran; mineral oil / |Inert atmosphere; |Reflux
2: hydrogenchloride / methanol / 14 h / 20 °C / |Inert atmosphere
View Scheme
参考文献
Zhao, Dongbing; Beiring, Bernhard; Glorius, Frank
Angewandte Chemie - International Edition, 2013 , vol. 52, # 32 p. 8454 - 8458
Angew. Chem., 2013 , vol. 125, # 32 p. 8612 - 8616,5
反应条件
sulfuric acid in ethanol
0.5 h; Heating;
参考文献
Lokhande; Ghiya
Journal of the Indian Chemical Society, 1991 , vol. 68, # 7 p. 412 - 413
反应条件
1: POCl3, pyridine
2: KOH / pyridine
View Scheme
参考文献
Nair, S. B.; Wadodkar, K. N.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 6 p. 573 - 574
反应条件
pyrrolidine in acetone; acetonitrile
参考文献
Hoechst Aktiengesellschaft
Patent: US6191164 B1, 2001 ;
US 6191164 B1
反应条件
in cyclohexane; acetone; acetonitrile
参考文献
Hoechst Marion Roussel Deutschland
Patent: US5955607 A1, 1999 ;
