2-羟基-5-甲基苯乙酮合成路线 （共 181 条）
反应条件
1: potassium hydroxide / ethanol; water / 20 °C 2: iodine / dimethyl sulfoxide / |Reflux View Scheme
参考文献
Sawant; Gill; Nirwan
Indian Journal of Heterocyclic Chemistry, 2012 , vol. 21, # 4 p. 297 - 300
反应条件
1: iodine 2: aqueous NaOH-solution; aq.-ethanolic NaOH-solution View Scheme
参考文献
Wittig
Chemische Berichte, 1924 , vol. 57, p. 92
Justus Liebigs Annalen der Chemie, 1926 , vol. 446, p. 157 Anm. 2, 177
反应条件
nitric acid in acetic acid 2.5 h; Ambient temperature;
参考文献
Synthesis, , # 11 p. 940 - 942
反应条件
methanecarbohydroxamic acid; sulfuric acid in acetonitrile T=80°C; P=1292.9 Torr; 0.133333 h; Microwave irradiation;
参考文献
Tetrahedron Letters, , vol. 52, # 46 p. 6103 - 6107
反应条件
1: ammonia / methanol / 2 h / 20 °C / Inert atmosphere 2: sodium hypochlorite / water; isopropyl alcohol / 0 - 10 °C / Inert atmosphere View Scheme
参考文献
Organic Letters, , vol. 13, # 23 p. 6300 - 6303
反应条件
ammonium acetate; acetic acid in benzene 6 h; Heating;
参考文献
Madkour, Hassan M. F.
Heterocycles, 1993 , vol. 36, # 5 p. 947 - 959
反应条件
sodium hydride in mineral oil T=0 - 100°C;
参考文献
Nolan, Karen A.; Doncaster, Jeremy R.; Dunstan, Mark S.; Scott, Katherine A.; Frenkel, A. David; Siegel, David; Ross, David; Barnes, John; Levy, Colin; Leys, David; Whitehead, Roger C.; Stratford, Ian J.; Bryce, Richard A.
Journal of Medicinal Chemistry, 2009 , vol. 52, # 22 p. 7142 - 7156
反应条件
triethylamine in tetrahydrofuran T=80°C; P=7355.08 Torr; 4 h;
参考文献
Mizuno, Takumi; Nishiguchi, Ikuzo; Hirashima, Tsuneaki; Ogawa, Akiya; Kambe, Nobuaki; Sonoda, Noboru
Synthesis, 1988 , # 3 p. 257 - 259
反应条件
1: 49 percent / PhN(Me)MgBr / diethyl ether / 3 h / 20 °C 2: 96 percent / conc. HCl / 24 h / 20 °C 3: 71 percent / KOH / methanol / 0.5 h / Heating View Scheme
参考文献
Sosnovskikh; Kutsenko; Ovsyannikov
Russian Chemical Bulletin, 2000 , vol. 49, # 3 p. 478 - 481
反应条件
1: aqueous NaOH; aqueous H2O2 2: sodium acetate / 140 - 150 °C View Scheme
参考文献
Ono; Imoto
Bulletin of the Chemical Society of Japan, 1936 , vol. 11, p. 127,131
Nippon Kagaku Kaishi, 1936 , vol. 57, p. 112,118
