2-羟基-5-氯苯乙酮合成路线 （共 106 条）
反应条件
potassium carbonate
T=132°C; 0.05 h; Microwave irradiation;
参考文献
Mondal, Rina; Gupta, Arpita Das; Mallik, Asok K.
Tetrahedron Letters, 2011 , vol. 52, # 39 p. 5020 - 5024
反应条件
potassium hydroxide in methanol
Claisen-Schmidt Condensation; 0.0333333 h; Microwave irradiation;
参考文献
Albogami, Abdullah Saad; Karama, Usama; Mousa, Ahmed Amine; Khan; Al-Mazroa, Sara Abdullah; Alkhathlan, Hamad Z.
Oriental Journal of Chemistry, 2012 , vol. 28, # 2 p. 619 - 626
反应条件
2: iodine; aqueous KI
View Scheme
参考文献
Moshfegh et al.
Helvetica Chimica Acta, 1957 , vol. 40, p. 1157,1164
反应条件
sodium hydroxide; sodium chloride; sulfuric acid in ethanol
参考文献
DAIICHI PHARMACEUTICAL CO., LTD.
Patent: EP1405852 A1, 2004 ;
Location in patent: Page 250 ;
EP 1405852 A1
反应条件
1: 75 percent / NaOH / methanol / 5 h / 0 °C
2: H2O2; NaOH / aq. methanol / 0 °C
3: HCl / H2O
View Scheme
参考文献
Gupta, Satish C.; Sharma, Somesh; Saini, Ashok; Dhawan, Som N.
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 16 p. 2391 - 2395
反应条件
1: 50 percent / Zn, HCl / ethanol / 54 h / Heating
2: 70 percent / sodium acetate / 2 h / Heating
View Scheme
参考文献
v. Auwers; Wittig
Chemische Berichte, 1924 , vol. 57, p. 1273
