2-羟基-5-氯苯乙酮合成路线 （共 106 条）
反应条件
pyridine; trichlorophosphate
2 h;
参考文献
Rangachari, K.; Mazumdar, A. K. D.; Banerji, K. D.
Journal of the Indian Chemical Society, 1980 , vol. 57, # 10 p. 1014 - 1016
反应条件
1: 65 percent / pyridine, POCl3 / 2 h
2: 60 percent / KOH, pyridine / 50 deg C, then rt. 2 h
View Scheme
参考文献
Rangachari, K.; Mazumdar, A. K. D.; Banerji, K. D.
Journal of the Indian Chemical Society, 1980 , vol. 57, # 10 p. 1014 - 1016
反应条件
1: 75 percent / NaOH / methanol / 5 h / 0 °C
2: 90 percent / I2 / dimethylsulfoxide / 0.17 h / Heating
View Scheme
参考文献
Gupta, Satish C.; Sharma, Somesh; Saini, Ashok; Dhawan, Som N.
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 16 p. 2391 - 2395
反应条件
sodium hydroxide; ethanol; water
参考文献
Kuhn; Hensel
Chemische Berichte, 1953 , vol. 86, p. 1333,1337
反应条件
sodium hydroxide in ethanol
T=0°C; 3 h;
参考文献
Gupta, Satish C.; Saini, Ashok; Kumar, Devinder; Yadav, Narender S.; Chand, Kuldeep; et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1995 , # 2 p. 177 - 184
反应条件
sodium hydroxide in ethanol
参考文献
Yang, Guangfu; Jiang, Xiaohua; Yang, Huazheng
Pest Management Science, 2002 , vol. 58, # 10 p. 1063 - 1067
参考文献
Ghosh, Chandra Kanta; Bhattacharyya, Samita; Ghosh, Chandreyi; Patra, Amarendra
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 20 p. 3005 - 3013
反应条件
pyrrolidine in methanol
Heating;
参考文献
Laras, Younes; Pietrancosta, Nicolas; Moret, Vincent; Marc, Sylvain; Garino, Cedrik; Rolland, Amandine; Monnier, Valerie; Kraus, Jean-Louis
Australian Journal of Chemistry, 2006 , vol. 59, # 11 p. 812 - 818
反应条件
1: 50percent NaH/mineral oil / tetrahydrofuran / Ambient temperature
2: 50percent NaH/mineral oil, 18 crown 6 / dioxane / 3 h / 65 °C
3: Redex CF resin
View Scheme
参考文献
Humbert; Dagnaux; Cohen; et al.
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 1 p. 67 - 78
反应条件
1: 50percent NaH/mineral oil / tetrahydrofuran / Ambient temperature
2: 50percent NaH/mineral oil, 18 crown 6 / dioxane / 3 h / 65 °C
3: Redex CF resin
View Scheme
参考文献
Humbert; Dagnaux; Cohen; et al.
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 1 p. 67 - 78
