1: methanol; 1-amino-1,2-carboxyethane With acetyl chloride T=20°C; 18 h; Cooling with ice; 2: With sodium carbonate in water 3: 1-[[(9H-fluoren-9-ylmethoxy)carbonyl]oxy]-2,5-pyrrolidinedione in 1,4-dioxane; water T=5 - 20°C;

1: With water; sodium carbonate in 1,4-dioxane T=5 - 20°C; Cooling with ice; 2: With hydrogenchloride in 1,4-dioxane; water

1: 86 percent / 4-(dimethylamino)pyridine; 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride 2: 92 percent / triethylsilane / Pd-C / methanol / 0.08 h View Scheme

sodium hydroxide in methanol; dichloromethane T=20°C; 0.166667 h;

sodium trimethyl-silanolate in tetrahydrofuran 24 h;