反应条件
1: 4.7 g / MeOH-d, Na / 250 h
2: 1.) 9-borabicyclo<3.3.1>nonane (9-BBN), 2.) 2-aminoethanol / 1.) THF, RT, 24 h, 2.) ether, a) RT, 80 min, b) -5 deg C, 1.5 h
View Scheme
参考文献
Dawson; Hobbs; Chan; Chao
Journal of Medicinal Chemistry, 1981 , vol. 24, # 10 p. 1214 - 1223
