1-(4-氯苯基)-3-丁烯-1-醇合成路线 （共 47 条）
反应条件
pentacarbonyliron(0) in benzene Barbier-type reaction; 2 h; Heating;
参考文献
Russian Journal of Organic Chemistry, , vol. 38, # 7 p. 1014 - 1017
反应条件
ammonium chloride; magnesium 12 h; Ambient temperature;
参考文献
Journal of Organic Chemistry, , vol. 64, # 9 p. 3230 - 3236
反应条件
Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 55, # 8 p. 2415 - 2420
反应条件
hydrogenchloride; benzene-1,2-diol; triethylamine 1.) 12 h, 60 deg C; 2.) Et2O, 1 h; Yield given. Multistep reaction;
参考文献
Chemical & Pharmaceutical Bulletin, , vol. 35, # 5 p. 2155 - 2157
反应条件
T=25°C; pH=7; 6 h; aq. phosphate buffer;
参考文献
Advanced Synthesis and Catalysis, , vol. 353, # 13 p. 2354 - 2358
反应条件
tris(triphenylphosphine)ruthenium(II) chloride in water T=90 - 100°C; Isomerization; 1 h;
参考文献
Wang, Dong; Chen, Dongli; Haberman, John X.; Li, Chao-Jun
Tetrahedron, 1998 , vol. 54, # 20 p. 5129 - 5142
反应条件
1: 98 percent / DCC / DMAP / CH2Cl2 / 12 h / 25 °C 2: 93 percent / DIBAL-H; pyridine; DMAP / CH2Cl2; hexane / -78 - 0 °C 3: 89 percent / SnBr4 / CH2Cl2 / 1 h / -78 °C 4: 72 percent / Bu3SnH / AIBN / toluene / 0.5 h / Heating 5: 82 percent / 2-(di-tert-butylphosphino)biphenyl / Pd2(dba)3 / toluene / 24 h / 110 °C 6: TFA / CH2Cl2 / 1 h / 0 - 20 °C 7: K2CO3 / acetone / 12 h / 20 °C 8: 72 percent / H2 / 10percent Pd/C / methanol; ethyl acetate / 7 h / 20 °C View Scheme
参考文献
Marumoto, Shinji; Jaber, James J; Vitale, Justin P; Rychnovsky, Scott D
Organic letters, 2002 , vol. 4, # 22 p. 3919 - 3922
