4-[(2,4-二甲氧基苯基)(Fmoc-氨基)甲基]苯氧乙酸合成路线 (共 7 条)
反应条件
potassium carbonate in 1,4-dioxane; water 3 h;
参考文献
Bioscience, Biotechnology, and Biochemistry, , vol. 56, # 9 p. 1506 - 1507
反应条件
1: 85 percent / NH2OH*HCl, triethylamine / methanol; H2O / 72 h / Heating 2: 98 percent / hydrogen / PtO2 / acetic acid / 336 h / 760 Torr 3: 84 percent / K2CO3 / dioxane; H2O / 3 h View Scheme
参考文献
Bioscience, Biotechnology, and Biochemistry, , vol. 56, # 9 p. 1506 - 1507
反应条件
1: 88 percent / K2CO3, KI / ethanol / 72 h / Heating 2: 91 percent / 2 N NaOH / ethanol / 16 h / Heating 3: 85 percent / NH2OH*HCl, triethylamine / methanol; H2O / 72 h / Heating 4: 98 percent / hydrogen / PtO2 / acetic acid / 336 h / 760 Torr 5: 84 percent / K2CO3 / dioxane; H2O / 3 h View Scheme
参考文献
Bioscience, Biotechnology, and Biochemistry, , vol. 56, # 9 p. 1506 - 1507
反应条件
1: 98 percent / hydrogen / PtO2 / acetic acid / 336 h / 760 Torr 2: 84 percent / K2CO3 / dioxane; H2O / 3 h View Scheme
参考文献
Bioscience, Biotechnology, and Biochemistry, , vol. 56, # 9 p. 1506 - 1507
反应条件
1: 91 percent / 2 N NaOH / ethanol / 16 h / Heating 2: 85 percent / NH2OH*HCl, triethylamine / methanol; H2O / 72 h / Heating 3: 98 percent / hydrogen / PtO2 / acetic acid / 336 h / 760 Torr 4: 84 percent / K2CO3 / dioxane; H2O / 3 h View Scheme
参考文献
Bioscience, Biotechnology, and Biochemistry, , vol. 56, # 9 p. 1506 - 1507
反应条件
1: 64 percent / POCl3, ZnCl2 / nitrobenzene / 3 h / 60 °C 2: 88 percent / K2CO3, KI / ethanol / 72 h / Heating 3: 91 percent / 2 N NaOH / ethanol / 16 h / Heating 4: 85 percent / NH2OH*HCl, triethylamine / methanol; H2O / 72 h / Heating 5: 98 percent / hydrogen / PtO2 / acetic acid / 336 h / 760 Torr 6: 84 percent / K2CO3 / dioxane; H2O / 3 h View Scheme
参考文献
Bioscience, Biotechnology, and Biochemistry, , vol. 56, # 9 p. 1506 - 1507
反应条件
1: 64 percent / POCl3, ZnCl2 / nitrobenzene / 3 h / 60 °C 2: 88 percent / K2CO3, KI / ethanol / 72 h / Heating 3: 91 percent / 2 N NaOH / ethanol / 16 h / Heating 4: 85 percent / NH2OH*HCl, triethylamine / methanol; H2O / 72 h / Heating 5: 98 percent / hydrogen / PtO2 / acetic acid / 336 h / 760 Torr 6: 84 percent / K2CO3 / dioxane; H2O / 3 h View Scheme
参考文献
Bioscience, Biotechnology, and Biochemistry, , vol. 56, # 9 p. 1506 - 1507