palladium hydroxide on carbon; hydrogen in methanol T=20°C; P=2280.15 Torr; 15 h;

Stage #1: <b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1098214', constants.ctx, '0')">hydrogenchloride</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '3587155', constants.ctx, '0')">water</a> <br />T=20&deg;C;&nbsp;20&nbsp;h;&nbsp;<br />Stage #2: <b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '4152656', constants.ctx, '0')">sodium cyanoborohydride</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '3587155', constants.ctx, '0')">water</a> <br />T=20&deg;C;&nbsp;0.583333&nbsp;h;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1.1: dichloromethane / |Molecular sieve<br />2.1: n-butyllithium; N,N,N',N',N'',N''-hexamethylphosphoric triamide / hexane; tetrahydrofuran / 0.33 h / 0 &deg;C / |Inert atmosphere<br />2.2: 0.5 h / 0 &deg;C / |Inert atmosphere<br />3.1: tetrahydrofuran / 1 h / 0 &deg;C / |Inert atmosphere<br />3.2: 0.33 h / 20 &deg;C / |Inert atmosphere<br />4.1: hydrogenchloride / water / 20 h / 20 &deg;C<br />4.2: 0.58 h / 20 &deg;C<br /> <br /> &nbsp;