1: 75 percent / H2 / Pt / ethyl acetate / 48 h / 760 Torr 2: 96 percent / Zn(BH4)2 / diethyl ether / 1) 0 deg C, 3 h, 2) rt, 24 h View Scheme

<b>Multi-step reaction with 2 steps<br /> </b>1: 95 percent / tetrahydrofuran / 4 h / Heating<br />2: 37 percent / LDA / tetrahydrofuran; hexane / 5 h / 0 deg C -&gt; 25 deg C<br /> <br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1: 60 percent / acetonitrile / 16 h / Heating<br />2: 1) n-BuLi / 1) THF, -30 deg C, 2 h, 2) THF, -78 deg C, 2 h, then -78 dec C -&gt; rt, 16 h<br />3: 95 percent / tetrahydrofuran / 4 h / Heating<br />4: 37 percent / LDA / tetrahydrofuran; hexane / 5 h / 0 deg C -&gt; 25 deg C<br /> <br /> &nbsp;