N-叔丁氧羰基-L-3-(2-呋喃基)丙氨酸合成路线 （共 14 条）
反应条件
1: 80 percent / dioxane / 39 h / Heating 2: 54 percent / KOH / ethanol; H2O / 17 h / Heating 3: 63 percent / cobalt acetate, 25percent aq. NH4OH / H2O / 38 °C / acylase I 4: 1M NaOH / H2O; dioxane View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 4 p. 1151 - 1158
反应条件
1: N,N,N',N'-tetramethylguanidine / dichloromethane / 1 h / -30 °C 2: (Z,Z)-cycloocta-1,5-diene(S,S-1,2-bis(2,5-dimethylphospholanyl)benzene)rhodium(I) tetrafluoroborate; hydrogen / methanol / 48 h / 40 °C / 30003 Torr 3: water; lithium hydroxide hydrate / tetrahydrofuran; methanol / 2 h / 0 °C View Scheme
参考文献
ChemBioChem, , vol. 11, # 12 p. 1720 - 1726
反应条件
1: N,N,N',N'-tetramethylguanidine / dichloromethane / 1 h / -30 °C 2: (Z,Z)-cycloocta-1,5-diene(S,S-1,2-bis(2,5-dimethylphospholanyl)benzene)rhodium(I) tetrafluoroborate; hydrogen / methanol / 48 h / 40 °C / 30003 Torr 3: water; lithium hydroxide hydrate / tetrahydrofuran; methanol / 2 h / 0 °C View Scheme
参考文献
ChemBioChem, , vol. 11, # 12 p. 1720 - 1726
反应条件
1: (Z,Z)-cycloocta-1,5-diene(S,S-1,2-bis(2,5-dimethylphospholanyl)benzene)rhodium(I) tetrafluoroborate; hydrogen / methanol / 48 h / 40 °C / 30003 Torr 2: water; lithium hydroxide hydrate / tetrahydrofuran; methanol / 2 h / 0 °C View Scheme
参考文献
ChemBioChem, , vol. 11, # 12 p. 1720 - 1726
