2-甲基-2-硫代异脲硫酸盐合成路线 （共 127 条）
参考文献
Braun; Randall
Journal of the American Chemical Society, 1934 , vol. 56, p. 2134
参考文献
Augstein,J. et al.
Journal of Medicinal Chemistry, 1967 , vol. 10, p. 391 - 400
反应条件
sodium hydroxide in 1,4-dioxane 18 h;
参考文献
Gers, Tomasz; Kunce, Danuta; Markowski, Pawel; Izdebski, Jan
Synthesis, 2004 , # 1 p. 37 - 42
反应条件
sodium hydroxide in 1,4-dioxane 48 h;
参考文献
Gers, Tomasz; Kunce, Danuta; Markowski, Pawel; Izdebski, Jan
Synthesis, 2004 , # 1 p. 37 - 42
反应条件
potassium carbonate in ethanol; water T=85°C;
参考文献
Yang, Ling-Ling; Li, Guo-Bo; Yan, Heng-Xiu; Sun, Qi-Zheng; Ma, Shuang; Ji, Pan; Wang, Ze-Rong; Feng, Shan; Zou, Jun; Yang, Sheng-Yong
European Journal of Medicinal Chemistry, 2012 , vol. 56, p. 30 - 38
反应条件
potassium hydroxide; sodium hydroxide in methanol; diethyl ether
参考文献
Nantermet, Philippe G.; Selnick, Harold G.; Barrow, James C.; Coburn, Craig; Burgey, Christopher; Robinson, Kyle A.; Lyle, Terry Alan
Patent: US2003/158218 A1, 2003 ;
US 20030158218 A1
反应条件
water; hydrazine hydrate Darstellung;
参考文献
Schering-Kahlbaum A.G.
Patent: DE463576 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 16, p. 2510
参考文献
Smith; Anzelmi
Journal of the American Chemical Society, 1935 , vol. 57, p. 2730
反应条件
1: With 1-methyl-pyrrolidin-2-one; N-ethyl-N,N-diisopropylamine; PyAOP; p-nitrophenylcarbonate resin T=20°C; 2: With 1-methyl-pyrrolidin-2-one; ammonia T=20°C; 3: With trifluoroacetic acid in dichloromethane T=20°C; 1.5 h;
参考文献
Dodd, Dharmpal S.; Zhao, Yufen
Tetrahedron Letters, 2001 , vol. 42, # 7 p. 1259 - 1262
反应条件
sodium acetate in DMF (N,N-dimethyl-formamide) T=80°C; 4 h;
参考文献
KUMIAI CHEMICAL INDUSTRY CO., LTD.; Ihara Chemical Industry Co., Ltd.
Patent: EP1439169 A1, 2004 ;
Location in patent: Page 95 ;
