1: 97 percent / quinoline, Lindlar catalyst, H2 / hexane / 8 h 2: 96 percent / 2,2,4-trimethyl-pentane / 5 h / Heating; in the dark 3: diethyl ether; tetrahydrofuran / 10 h / Ambient temperature 4: TBAF / tetrahydrofuran / 24 h / Ambient temperature; in the dark View Scheme

1: 97 percent / quinoline, Lindlar catalyst, H2 / hexane / 8 h 2: 96 percent / 2,2,4-trimethyl-pentane / 5 h / Heating; in the dark View Scheme

<b>Multi-step reaction with 5 steps<br /> </b>1: 96 percent / Ph₃P, imidazole, I₂ / tetrahydrofuran / -20 deg C, 15 min then RT, 1.5 h<br />2: 90 percent / PDC / CH₂Cl₂ / 6 h / Ambient temperature<br />3: 92 percent / LDA / tetrahydrofuran / 2 h / -78 &deg;C<br />4: 65 percent / CuI, Zn / ethanol; H₂O / 0.67 h / sonication<br />5: 86 percent / Et₃N / (Ph₃P)2PdCl₂ / dimethylformamide / 1 h / 75 &deg;C<br /> <br /> &nbsp;