1: triethylamine / dichloromethane / 2 h / 0 - 20 °C 2: water; tetrahydrofuran / 3 h / 65 °C 3: tetrabutyl ammonium fluoride / tetrahydrofuran / 3 h / 20 °C View Scheme

<b>Multi-step reaction with 3 steps<br /> </b>1.1: 1H-imidazole / N,N-dimethyl-formamide / 0 &deg;C / |Inert atmosphere<br />2.1: sodium periodate / diethyl ether; water / 0.25 h<br />2.2: 48 h<br />3.1: sodium tetrahydroborate / methanol / 0.25 h / 0 &deg;C / |Inert atmosphere<br /> <br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1.1: C₂₈H₃₀N₂O₃; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 13 h / -40 &deg;C / |Inert atmosphere<br />2.1: 1H-imidazole / N,N-dimethyl-formamide / 0 &deg;C / |Inert atmosphere<br />3.1: sodium periodate / diethyl ether; water / 0.25 h<br />3.2: 48 h<br />4.1: sodium tetrahydroborate / methanol / 0.25 h / 0 &deg;C / |Inert atmosphere<br /> <br /> &nbsp;