hydrogen; acetic acid; platinum(IV) oxide T=60°C; 24 h;

1: H2 (cat.) 2: pyridine 3: 1.) e(1-) 2.) Et3O(1+)*BF4(1-) / 1.) MeOH 4: 5N HCl / Heating View Scheme

1: pyridine 2: 1.) e(1-) 2.) Et3O(1+)*BF4(1-) / 1.) MeOH 3: 5N HCl / Heating View Scheme

hydrogenchloride Heating;

1: 1.) PCl5, SO2Cl2 2.) H2, Et3N / 1.) CHCl3, reflux 2.) Raney-Ni, ethanol 2: Ba(OH)2.8H2O / 2 h / Heating View Scheme

1: 1.) e(1-) 2.) Et3O(1+)*BF4(1-) / 1.) MeOH 2: 5N HCl / Heating View Scheme

barium dihydroxide 2 h; Heating; Yield given. Yields of byproduct given;

1: in dichloromethane T=0 - 5°C; 2 h; 2: With acetic acid in water Product distribution / selectivity;

1: N-[(S)-1-carbethoxy-3-phenyl-propyl]-S-alaninoyl chloride hydrochloride With 1H-imidazole in dichloromethane T=-5 - 0°C; 1 h; 2: (2S,3aR,7aS)-octahydroindolecarboxylic acid in dichloromethane T=-5 - 25°C; 4.75 h; 3: With acetic acid in dichloromethane; water T=5°C; 0.5 h; Product distribution / selectivity;