N-Boc-4-碘甲基哌啶合成路线 （共 13 条）
反应条件
diisopropylamine in tetrahydrofuran; 5,7-dihydro-3-methyl-6H-pyrrololt;3,2-fgt;-1,2-benzisoxazol-6-one
参考文献
Pfizer Inc.
Patent: US5538984 A1, 1996 ;
US 5538984 A
反应条件
potassium carbonate; sodium thiosulfate in water; toluene
参考文献
Merck and Co., Inc.
Patent: US6265434 B1, 2001 ;
US 6265434 B1
反应条件
1: 5,6-Dimethoxy-1-oxoindane-2-carboxylic acid methyl ester With potassium carbonate in N,N-dimethyl-formamide
T=20°C; 0.5 h;
2: 4-iodomethyl-piperidine-1-carboxylic acid tert-butyl ester in DMF (N,N-dimethyl-formamide)
T=20 - 50°C; 5.5 h;
参考文献
CHEMAGIS LTD.
Patent: EP1386607 A1, 2004 ;
Location in patent: Page/Page column 10 ;
