3-氨基-6-氯吡嗪-2-甲酸甲酯合成路线 (共 4 条)
反应条件
trichlorophosphate in N,N-dimethyl-formamide T=20°C; 0.5 h;
参考文献
WO2008/9908 A1, ;
Page/Page column 64-65 ;
反应条件
chlorine in water; acetic acid
反应条件
sodium hydroxide in diphenylether; water
参考文献
Zeneca Limited
Patent: US5866568 A1, 1999 ;
反应条件
sodium chloride; sodium nitrite in tetrahydrofuran; hydrogenchloride; water; ethyl acetate
参考文献
Toyama Chemical Co., Ltd.
Patent: US2003/130213 A1, 2003 ;