2-(苯并[b]噻吩-3-基)乙胺合成路线 （共 6 条）
反应条件
samarium diiodide; water; triethylamine in tetrahydrofuran T=20°C; 0.0833333 h; Inert atmosphere;
参考文献
Szostak, Michal; Sautier, Brice; Spain, Malcolm; Procter, David J.
Organic Letters, 2014 , vol. 16, # 4 p. 1092 - 1095
反应条件
trifluoroacetic acid in dichloromethane T=20°C; 24 h;
参考文献
BAYER CROPSCIENCE SA
Patent: WO2007/6739 A1, 2007 ;
Location in patent: Page/Page column 73 ;
反应条件
1: 28 percent / benzyltriethylammonium chloride / H2O / 1 h / 90 - 95 °C 2: LiAlH4, AlCl3 / diethyl ether / 22 h / Heating View Scheme
参考文献
Efange, Simon M. N.; Mash, Deborah C.; Khare, Anil B.; Ouyang, Quinjie
Journal of Medicinal Chemistry, 1998 , vol. 41, # 23 p. 4486 - 4491
反应条件
1: 90.7 percent / HCl / H2O / 1.5 h / 65 °C 2: 28 percent / benzyltriethylammonium chloride / H2O / 1 h / 90 - 95 °C 3: LiAlH4, AlCl3 / diethyl ether / 22 h / Heating View Scheme
参考文献
Efange, Simon M. N.; Mash, Deborah C.; Khare, Anil B.; Ouyang, Quinjie
Journal of Medicinal Chemistry, 1998 , vol. 41, # 23 p. 4486 - 4491
反应条件
lithium aluminium tetrahydride; diethyl ether
参考文献
Herz
Journal of the American Chemical Society, 1950 , vol. 72, p. 4999
反应条件
hydrogenchloride in methanol
参考文献
MIKANA THERAPEUTICS, INC.
Patent: WO2006/88949 A1, 2006 ;
Location in patent: Page/Page column 170-172 ;
