反应条件
1: H2 / Rh/Al2O3
2: 1.) LDA, 2.) I2 / 1.) THF, hexane, from -78 to 0 deg C, 2.5 h, 2.) THF, hexane, from -78 deg C to RT
3: aq. KOH / methanol / Heating
4: 1.) HgO, 2.) Br2 / 1.) CH2Cl2, reflux, irradiation, 2.) CH2Cl2, reflux
5: 1.) tert-BuLi / 1.) THF, pentane, -78 deg C, 5 min, 2.) THF, pentane, from -78 deg C to RT
View Scheme
参考文献
Wiberg, Kenneth B.; Artis, Dean R.; Bonneville
Journal of the American Chemical Society, 1991 , vol. 113, # 21 p. 7969 - 7979
