1: oxalyl dichloride; cycloheptane carboxylic acid With N,N-dimethyl-formamide in dichloromethane T=20°C; 1 h; 2: diazomethyl-trimethyl-silane in tetrahydrofuran; diethyl ether T=0°C; 3: With hydrogen bromide; sodium carbonate more than 3 stages;
参考文献
Li, James J.; Hamann, Lawrence G.; Wang, Haixia
Patent: US2006/281750 A1, 2006 ;
Location in patent: Page/Page column 27 ;