(R)-(-)-2-氨基-2-甲基丁二酸合成路线 (共 4 条)
反应条件
hydrogen bromide in water 12 h; RefluxInert atmosphere;
参考文献
Branca, Mathieu; Pena, Sebastien; Guillot, Regis; Gori, Didier; Alezra, Valerie; Kouklovsky, Cyrille
Journal of the American Chemical Society, 2009 , vol. 131, # 30 p. 10711 - 10718
反应条件
1: aq. NaOH / methanol / 20 °C 2: H2 / Pd/C / ethanol / 36 h / 40 °C / 30400 Torr View Scheme
参考文献
Tetrahedron, , vol. 57, # 30 p. 6361 - 6366
反应条件
(i) O3, AcOH, (ii) aq. H2O2, (iii) aq. HCl; Multistep reaction;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 14, p. 1138 - 1143
反应条件
Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Tetrahedron Letters, , vol. 29, # 4 p. 403 - 406