2-(5-(1-(甲氧基甲氧基)乙基)吡啶-2-基)乙醇合成路线 (共 1 条)
反应条件
1: 62 percent / diethyl azodicarboxylate, Ph3P / tetrahydrofuran / 18 h / Ambient temperature 2: 58 percent / piperidine / ethanol / 18 h / Heating 3: 61 percent / NaBH4, 1.0N aq. NaOH, CoCl2*6H2O, 2,2'-dipyridyl / dimethylformamide / 42 h / Ambient temperature 4: 98 percent / 2N aq. HCl / methanol / 2 h / Heating View Scheme
参考文献
Sohda; Ikeda; Meguro
Chemical and Pharmaceutical Bulletin, 1995 , vol. 43, # 12 p. 2168 - 2172