中-四(4-羧基苯基)卟吩合成路线 （共 9 条）
反应条件
propionic acid Condensation; 0.5 h; Heating;
参考文献
Suarez, Margarita; Salfran, Esperanza; Curiel, Rene I. Rodriguesz; Elguero, Jose
Bulletin des Societes Chimiques Belges, 1997 , vol. 106, # 4 p. 211 - 214
反应条件
water; potassium hydroxide in tetrahydrofuran; methanol T=40°C; 1 h;
参考文献
Gianferrara, Teresa; Bergamo, Alberta; Bratsos, Ioannis; Milani, Barbara; Spagnul, Cinzia; Sava, Gianni; Alessio, Enzo
Journal of Medicinal Chemistry, 2010 , vol. 53, # 12 p. 4678 - 4690
反应条件
1: With propionic acid 3 h; Heating / reflux; 2: With sodium hydrogencarbonate in water 3: With hydrogenchloride in water pH=< 6;
参考文献
US6730666 B1, ;
Page/Page column 20 ;
US 6730666 B1
反应条件
sodium hydroxide in tetrahydrofuran; methanol
参考文献
Organic and Biomolecular Chemistry, , vol. 10, # 24 p. 4782 - 4787
反应条件
1: 5,10,15,20-tetrakis(4-carboxyphenyl)porphyrin With hydroxylamine hydrochloride T=100 - 160°C; 3 h; 2: methanol With sulfuric acid T=20°C; 36 h; Reflux;
参考文献
Rudine, Alexander B.; Delfatti, Brian D.; Wamser, Carl C.
Journal of Organic Chemistry, 2013 , vol. 78, # 12 p. 6040 - 6049
反应条件
1: chlorinating agent / |Inert atmosphere
2: |Inert atmosphere
View Scheme
参考文献
Presolski, Stanislav I.; Van Der Weegen, Rob; Wiesfeld, Jan J.; Meijer
Organic Letters, 2014 , vol. 16, # 7 p. 1864 - 1867
反应条件
1: SOCl2; pyridine / 4 h / Heating
View Scheme
参考文献
Gauuan, Polivina Jolicia F; Trova, Michael P; Gregor-Boros, Livia; Bocckino, Stephen B; Crapo, James D; Day, Brian J
Bioorganic and medicinal chemistry, 2002 , vol. 10, # 9 p. 3013 - 3021
参考文献
Abraham, Raymond J.; Marsden, Ian; Xiujing, Lucy
Magnetic Resonance in Chemistry, 1990 , vol. 28, # 12 p. 1051 - 1057
反应条件
1: 5,10,15,20-tetrakis(4-carboxyphenyl)porphyrin With hydroxylamine hydrochloride
T=100 - 160°C; 3 h;
2: methanol With sulfuric acid
T=20°C; 36 h; Reflux;
参考文献
Rudine, Alexander B.; Delfatti, Brian D.; Wamser, Carl C.
Journal of Organic Chemistry, 2013 , vol. 78, # 12 p. 6040 - 6049
